Curcumin down regulates homeobox gene NKX3.1 in prostate cancer cell LNCaP
β Scribed by Hui-na ZHANG; Chun-xiao YU; Peng-ju ZHANG; Wei-wen CHEN; An-li JIANG; Feng KONG; Jing-ti DENG; Jian-ye ZHANG; Charles YF YOUNG
- Book ID
- 111355149
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- Chinese
- Weight
- 792 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1671-4083
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract __NKX3.1__ is a homeobox gene, expression of which is largely restricted to the adult prostatic epithelium. Loss of NKX3.1 expression has been linked to prostate carcinogenesis and disease progression and occurs in the absence of mutations in the coding region of the __NKX3.1__ gene. In
## Abstract Although it is often presumed that the molecular pathways that underlie normal organogenesis are similar to those perturbed during carcinogenesis, few examples exist of tissueβspecific regulatory genes that play central roles in both processes. In the case of the prostate gland, molecul
## Abstract Androgenβregulated genes (ARG) are implicated in normal and neoplastic growth of the prostate. Recently, we reported genomic amplification and/or overexpression of a previously known neurotrophic factor, prosaposin, in androgenβindependent (AI) or metastatic prostate cancer (PCa) cells