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Curcumin attenuates indomethacin-induced oxidative stress and mitochondrial dysfunction

✍ Scribed by Nageswaran Sivalingam; Jayasree Basivireddy; Kunissery A. Balasubramanian; Molly Jacob

Publisher: Springer-Verlag
Year: 2007
Tongue: English
Weight: 560 KB
Volume: 82
Category: Article
ISSN: 0340-5761
DOI: 10.1007/s00204-007-0263-9

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## Abstract We analyzed the effects of corticosteroid on mitochondrial membrane potentials (ΔΨ~m~), generation of reactive oxygen species (ROS), and apoptosis in a human rhabdomyosarcoma cell line, RD, and a dopaminergic neuroblastoma cell line, SH‐SY5Y. The cell lines were cultured in the presence