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Cultures derived from peripheral blood CD34+ progenitor cells of head and neck cancer patients and from cord blood are functionally different

✍ Scribed by Deanne M.R. Lathers; Eve Lubbers; Nicole M. Beal; Mark A. Wright; M.Rita I. Young

Book ID
117415944
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
384 KB
Volume
60
Category
Article
ISSN
0198-8859

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Patients with head and neck squamous cell carcinoma (HNSCC) have profound immune deficiencies. In 65% of these patients, there is an increased intra-tumoral presence of immune-suppressive CD34 Ψ‰ progenitor cells. The goal of the present study was to determine whether CD34 Ψ‰ cell levels were also inc