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Cultured retinal pericytes stimulate in vitro angiogenesis of endothelial cells through secretion of a fibroblast growth factor-like molecule

✍ Scribed by Satoe Watanabe; Nobuhiro Morisaki; Mariko Tezuka; Kuniaki Fukuda; Shirou Ueda; Noriyuki Koyama; Koutaro Yokote; Tetsuto Kanzaki; Sho Yoshida; Yasushi Saito


Book ID
119436300
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
349 KB
Volume
130
Category
Article
ISSN
0021-9150

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High and low affinity binding sites for
✍ David Moscatelli πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 834 KB

Scatchard analysis of binding of 125I-basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the presence of two binding sites: a high affinity site with KD of 20 pM and 80,000 sites per cell and a low affinity site with KD of about 2 nM and 600,000 sites per cell. The bind