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Cultured Human-Cell-Based Bioassay for Environmental Risk Management

✍ Scribed by Y. Sakai; R. Shoji; B.-S. Kim; A. Sakoda; M. Suzuki


Book ID
110294476
Publisher
Springer
Year
2001
Tongue
English
Weight
293 KB
Volume
70
Category
Article
ISSN
0167-6369

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## Abstract The feasibility of detection of carcinogenic chemicals using DNA repair synthesis of cultured human fibroblasts as measured by an unscheduled ^3^HTdR incorporation has been explored. Of 64 chemicals tested, 29 were proximate or ultimate carcinogens, 15 were precarcinogens that required