## Abstract Cartilage implants for potential use in reconstructive or orthopedic surgery can be created by growing isolated cartilage cells (chondrocytes) in vitro on synthetic, biodegradable polymer scaffolds. The scaffolds provide specific three‐dimensional structures which support cell prolifera
Cultivation of cell-polymer cartilage implants in bioreactors
✍ Scribed by L. E. Freed; G. Vunjak-Novakovic; R. Langer
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 834 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0730-2312
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Tissue engineered cartilage can be grown in vitro if the necessary physical and biochemical factors are present in the tissue culture environment. Cell metabolism and tissue composition were studied for engineered cartilage cultured for 5 weeks using bovine articular chondrocytes, polymer scaffolds
## Abstract The aim of our study was to evaluate the mid‐term outcome of a cell‐free polymer‐based cartilage repair approach in a sheep cartilage defect model in comparison to microfracture treatment. Cell‐free, freeze‐dried implants (chondrotissue®) made of a poly‐glycolic acid (PGA) scaffold and
Cartilaginous constructs have been grown in v i f m with use of isolated cells, biodegradable polymer scaffolds, and bioreactors. In the present work, the relationships between the composition and mechanical properties of engineered cartilage constructs were studied by culturing bovine calf articula