✦ LIBER ✦

CuCl-Catalyzed Aerobic Oxidation of Allylic and Propargylic Alcohols to Aldehydes or Ketones with 1:1 Combination of Phenanthroline and Bipyridine as the Ligands

✍ Scribed by Yu Liu; Shengming Ma

Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 359 KB
Volume: 30
Category: Article
ISSN: 0256-7660
DOI: 10.1002/cjoc.201100476

No coin nor oath required. For personal study only.

✦ Synopsis

We developed a modified protocol for the oxidation of 2,3-allenyl alcohols using CuCl with 1∶1 combination of phenanthroline and bipyridine as the catalyst. To further investigate the applicability of this system, other types of alcohols such as allylic and propargylic alcohols have been tested: we found that both allylic and propargylic alcohols may be oxidized to the corresponding aldehydes or ketones using molecular oxygen in air as the oxidant with moderate to excellent yields.