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Cubic phases for studies of drug partition into lipid bilayers

✍ Scribed by Sven Engström; Tomas Petersson Nordén; Håkan Nyquist


Book ID
114303197
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
290 KB
Volume
8
Category
Article
ISSN
0928-0987

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The design of liposomal delivery systems for hydrophobic drug molecules having improved encapsulation efficiency and enhanced drug retention would be highly desirable. Unfortunately, the poor aqueous solubility and high membrane binding affinity of hydrophobic drugs necessitates extensive validation