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Cu2+ Inhibits the Aggregation of Amyloid β-Peptide(1–42) in vitro

✍ Scribed by Jin Zou; Katsushi Kajita; Naoki Sugimoto

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
100 KB
Volume
40
Category
Article
ISSN
0044-8249

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Cu2+ Inhibits the Aggregation of Amyloid
Cu2+ Inhibits the Aggregation of Amyloid β-Peptide(1–42) in vitro
✍ Jin Zou; Katsushi Kajita; Naoki Sugimoto 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB

Alzheimers disease (AD) is the most frequent cause of late-life dementia, with pathological characteristics of extracellular aggregation of amyloid b-peptides (Abs) with 39 ± 43 amino acids, which are proteolytically derived from the transmembrane amyloid precursor protein (APP). [1] Recent studies