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CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice

✍ Scribed by Mitsuyoshi Takiguchi; Masaaki Murakami; Izumi Nakagawa; Izumu Saito; Akira Hashimoto; Toshimitsu Uede

Book ID
117176699
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
800 KB
Volume
66
Category
Article
ISSN
0024-3205

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IK cytokine ameliorates the progression
IK cytokine ameliorates the progression of lupus nephritis in MRL/lpr mice
✍ Masatake Muraoka; Hitoshi Hasegawa; Masashi Kohno; Atsushi Inoue; Tatsuhiko Miya πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 442 KB πŸ‘ 1 views

## Abstract ## Objective IK cytokine has been isolated as a factor that inhibits interferon‐γ (IFNΞ³)–induced expression of class II major histocompatibility complex (MHC) antigens. Aberrant expression of class II MHC antigens has reportedly been recognized in the target organs of autoimmune diseas