✦ LIBER ✦

CTLA4/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population

✍ Scribed by Erin J. Walker; Gideon M. Hirschfield; Chun Xu; Yan Lu; Xiangdong Liu; Yue Lu; Catalina Coltescu; Kesheng Wang; William G. Newman; Vivian Bykerk; Edward C. Keystone; Dianne Mosher; Christopher I. Amos; E. Jenny Heathcote; Katherine A. Siminovitch

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 206 KB
Volume: 60
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.24412

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Haplotype analysis in simplex families a

Haplotype analysis in simplex families and novel analytic approaches in a case–control cohort reveal no evidence of association of the CTLA-4 gene with rheumatoid arthritis

✍ Anne Barton; Francine Jury; Stephen Eyre; John Bowes; Anne Hinks; Daniel Ward; J 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 63 KB 👁 1 views

## Abstract ## Objective Cytotoxic T lymphocyte–associated antigen 4 (CTLA‐4) is a negative regulator of T cells and is, therefore, a strong candidate susceptibility gene for T cell–mediated autoimmune diseases. The association of CTLA‐4 single‐nucleotide polymorphisms (SNPs) with rheumatoid arthr