CD28 and CTLA-4 are opposing regulators of T cell activation, triggered by the two ligands CD80 and CD86. How these ligands promote either T cell activation via CD28 or inhibition via CTLA-4 is not understood. Using CD80 and CD86 molecules expressed on transfected cells, we have identified a major d
β¦ LIBER β¦
CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation
β Scribed by Dorothy K. Sojka; Angela Hughson; Deborah J. Fowell
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 208 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0014-2980
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