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CTGF inhibits cell motility and COX-2 expression in oral cancer cells

โœ Scribed by Jing-Yuan Chuang; Wan-Yu Yang; Chih-Ho Lai; Chia-Der Lin; Ming-Hsui Tsai; Chih-Hsin Tang


Book ID
116576869
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
717 KB
Volume
11
Category
Article
ISSN
1567-5769

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Cyclooxygenase (COX)-2 is one of the rate-limiting enzymes in the conversion of arachidonic acid to prostaglandins and other eicosanoids. Recent studies have shown enhanced expression of COX-2 in cancer cells of several tissues. We investigated the expression of COX-2 and prostaglandin (PG) E 2 prod