Increased binding of SP1 to the γ-globin
✍
Pritam K. Sengupta; Donald Lavelle; Dr. Joseph Desimone
📂
Article
📅
1994
🏛
John Wiley and Sons
🌐
English
⚖ 400 KB
👁 1 views
## Abstract We have studied the effect of site‐specific cytosine methylation on the binding of nuclear proteins to the γ‐globin promoter region from −71 to −34. This sequence was recently shown to contain a stage selector element responsible for increased transcription from the γ compared to the β