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CSF levels of YKL-40 are increased in MS and decrease with immunosuppressive treatment

✍ Scribed by Malmeström, Clas; Axelsson, Markus; Lycke, Jan; Zetterberg, Henrik; Blennow, Kaj; Olsson, Bob

Book ID
122178303
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
294 KB
Volume
269
Category
Article
ISSN
0165-5728

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## Abstract YKL‐40 is a glycoprotein secreted by macrophages, neutrophils and malignant tumor cells. Elevated serum levels of YKL‐40 are associated with poor prognosis in several malignancies. In this study, we examined the prognostic value of serum YKL‐40 before treatment and during follow‐up in p