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CS1-7 Activated fibrocytes contribute to disease pathogenesis in rheumatoid arthritis

✍ Scribed by Carole L. Galligan; Katherine Siminovitch; Edward Keystone; Vivian Bykerk; Omar Perez; Eleanor Fish

Book ID
116399527
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
39 KB
Volume
52
Category
Article
ISSN
1043-4666

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## Abstract ## Objective To investigate whether protease‐activated receptor 1 (PAR‐1) and/or PAR‐2 promotes the invasiveness/proliferation of synovial fibroblasts (SFs) and to determine the signaling mechanisms of these pathways. ## Methods SFs were isolated from the synovial tissue of patients