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CS1-1 IL-7 signaling and the control of B cell development

โœ Scribed by Harinder Singh


Book ID
116399521
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
132 KB
Volume
52
Category
Article
ISSN
1043-4666

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## Abstract The cytokine ILโ€7 and its receptor are essential for normal B and Tโ€„lymphopoiesis. We have analyzed the role of this receptor in Bโ€„cell development throughout ontogeny in ILโ€7 receptorโ€„ฮฑโ€deficient mice. We demonstrate that the ILโ€7 receptor becomes progressively more important with age.