Impaired B-1 and B-2 B cell development
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Lena Erlandsson; Steve Licence; Fabrina Gaspal; Sarah Bell; Peter Lane; AnneโE.
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Article
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2004
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John Wiley and Sons
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English
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## Abstract The cytokine ILโ7 and its receptor are essential for normal B and Tโlymphopoiesis. We have analyzed the role of this receptor in Bโcell development throughout ontogeny in ILโ7 receptorโฮฑโdeficient mice. We demonstrate that the ILโ7 receptor becomes progressively more important with age.