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Crystallographic determination of the stereochemistry of C-6,7 epoxy paclitaxel

โœ Scribed by Thomas J. Altstadt; Qi Gao; Mark D. Wittman; John F. Kadow; Dolatrai M. Vyas

Book ID
104259476
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
156 KB
Volume
39
Category
Article
ISSN
0040-4039

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AbstractรStructure modiยฎcation of paclitaxel at the C-6 and C-7 positions has been achieved using the readily available intermediate 6ahydroxy-7-epipaclitaxel (2). While a single diastereomer of the cyclic sulยฎte of 2 was prepared at lower temperature, both diastereomers were obtained at room temper