Crystallized p-toluene sulfonate diacetylenic lipid: a Raman spectroscopic study

✍ Scribed by Paul E. Schoen; Feredoon Behroozi; Bruce P. Gaber; Albert Hybl; Alok Singh

• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 600 KB
• Volume: 62
• Category: Article
• ISSN: 0009-3084
• DOI: 10.1016/0009-3084(92)90091-3

✦ Synopsis

The diacetylenic lipid, 1,2-bis-(tricosa 10,12 diynoyl)-rac-glycero-3-(-p-toluene-sulfonate), which is related to the tubule-forming lipid, 1,2-bis-(tricosa 10,12 diynoyl)-sn-glycero-3-phosphocholine, has been synthesized and crystallized. The monoclinic crystal structures were polymerized by UV light and displayed strong red coloration when illuminated with light polarized along the crystalline a axis. Raman and resonance Raman spectra of the crystallized lipid were obtained as a function of its degree of polymerization. Spectral features sensitive to order in the lipid hydrocarbon chains reveal that the chains are highly ordered and that this order persists as polymerization proceeds.