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Crystallization of antibody fragments and their complexes with antigen

โœ Scribed by G. Boulot; V. Guillon; R.A. Mariuzza; R.J. Poljak; M.-M. Riottot; H. Souchon; S. Spinelli; D. Tello

Book ID
107790125
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
876 KB
Volume
90
Category
Article
ISSN
0022-0248

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The application of microseed matrix screening to the crystallization of antibodyโ€“antigen complexes is described for a set of antibodies that include mouse anti-IL-13 antibody C836, its humanized version H2L6 and an affinity-matured variant of H2L6, M1295. The Fab fragments of these antibodies were c