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Crystallization of a Desired Metastable Polymorph by Pseudoseeding, Crystal Structure Solution from Its Powder X-ray Diffraction Data, and Confirmation of Polymorphic Transition

✍ Scribed by Miura, Hidenori; Ushio, Takaniro; Nagai, Keiko; Fujimoto, Daisuke; Lepp, Zsolt; Takahashi, Hiroki; Tamura, Rui


Book ID
111951800
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
173 KB
Volume
3
Category
Article
ISSN
1528-7483

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Ranitidine hydrochloride (RAN-HCl), a known anti-ulcer drug, is the product of reaction between HCl and ranitidine base (RAN-B). RAN-HCl has been extensively studied; however this is not the case of the RAN-B. The solid state characterization of RAN-B polymorphs has been carried out using different