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Crystallization and preliminary crystallographic study of cathepsin D inhibitor from potatoes

✍ Scribed by Miroslav Baudyš; Minakshi Ghosh; Karl Harlos; Michael Mareš; Martin Fusek; Vladimír Kostka; Colin C.F. Blake


Book ID
118919005
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
202 KB
Volume
218
Category
Article
ISSN
0022-2836

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## Abstract Cathepsin K is a cysteine protease of the papain family, which is predominantly expressed in osteoclasts, and is regarded as a key protease in bone remodeling. To facilitate structural studies of the protein, the wild‐type sequence of the protease has been mutated so as to replace a pot