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Crystallization and crystallographic investigations of ribonucleotide reductase protein R1 from Escherichia coli

✍ Scribed by Ulla Uhlin; Tomas Uhlin; Hans Eklund


Book ID
115928666
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
602 KB
Volume
336
Category
Article
ISSN
0014-5793

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Conformation of dCDP Bound to Protein R1
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Deoxycytidine 5'-diphosphate (dCDP) is a product and competitive inhibitor of ribonucleoside-diphosphate reductase (EC 1.17.4.1) from Escherichia coli. Its conformation in the enzyme-bound state is of importance for understanding the reaction mechanism. Free and bound dCDP are in fast exchange and t