Crystalline anhydrous trimethylamine N-oxide

✍ Scribed by John A. Soderquist; Charles L. Anderson

• Book ID: 104218964
• Publisher: Elsevier Science
• Year: 1986
• Tongue: French
• Weight: 166 KB
• Volume: 27
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)84884-4

✦ Synopsis

A rapid, efficient procedure for the preparation of pure, crystalline anhydrous trimethylamine N-oxide from the com.mercially available dihydrate form of the reagent is describ;d. DMF serves to both allow the distillative removal of water as well as to provide an excellent medium for obtaining large crystals of the pure (.mp 225-7'C (dec)), anhydrous material in excellent (94%) yield.