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Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgamma S

✍ Scribed by Cherfils, J.


Book ID
111745014
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
734 KB
Volume
16
Category
Article
ISSN
0261-4189

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Structure of the small G protein Rap2 in
✍ J. MΓ©nΓ©trey; J. Cherfils πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 376 KB πŸ‘ 1 views

We report a novel crystal form of the small G protein Rap2A in complex with GTP which has no GTPase activity in the crystal. The asymmetric unit contains two complexes which show that a conserved switch I residue, Tyr 32, contributes an extra hydrogen bond to the β₯-phosphate of GTP as compared to re