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Crystal Structures of the MthK RCK Domain Reveal Allosteric Interactions Among Calcium Binding Sites

✍ Scribed by Smith, Frank J.; Rothberg, Brad S.

Book ID
122191336
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
40 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract An optimised method of solution cyclisation gave us access to a series of peptides including SLKIDNLD (**2**). We investigated the crystallographic complexes of the HIV integrase (HIV‐IN) catalytic core domain with 13 of the peptides and identified multiple interactions at the binding s