✦ LIBER ✦

Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog

✍ Scribed by Suto, Kyoko; Shimizu, Yoshihiro; Watanabe, Kazunori; Ueda, Takuya; Fukai, Shuya; Nureki, Osamu; Tomita, Kozo

Book ID: 110031815
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 438 KB
Volume: 25
Category: Article
ISSN: 0261-4189
DOI: 10.1038/sj.emboj.7601433

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Leucyl/phenylalanyl(L/F)-tRNA-protein tr

Leucyl/phenylalanyl(L/F)-tRNA-protein transferase-mediated aminoacyl transfer of a nonnatural amino acid to the N-terminus of peptides and proteins and subsequent functionalization by bioorthogonal reactions

✍ Masumi Taki; Masahiko Sisido 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 236 KB

## Abstract We report here a new strategy for derivatizing peptides and proteins at the N‐terminus. To achieve this, a nonnatural amino acid was charged onto a tRNA and then enzymatically transferred to a lysine (Lys) unit at the N‐terminus of a peptide or a protein by using L/F‐tRNA‐protein transf

Leucyl/Phenylalanyl-tRNA-Protein Transfe

Leucyl/Phenylalanyl-tRNA-Protein Transferase-Mediated Chemoenzymatic Coupling of N-Terminal Arg/Lys Units in Post-translationally Processed Proteins with Non-natural Amino Acids

✍ Masumi Taki; Atsushi Kuno; Shinsuke Matoba; Yuki Kobayashi; Junichiro Futami; Hi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB

Idiosyncrasy and identity in the prokary

Idiosyncrasy and identity in the prokaryotic phe-system: Crystal structure of E. coli phenylalanyl-tRNA synthetase complexed with phenylalanine and AMP

✍ Inbal Mermershtain; Igal Finarov; Liron Klipcan; Naama Kessler; Haim Rozenberg; 📂 Article 📅 2010 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 360 KB

## Abstract The crystal structure of Phenylalanyl‐tRNA synthetase from __E. coli__ (__Ec__PheRS), a class II aminoacyl‐tRNA synthetase, complexed with phenylalanine and AMP was determined at 3.05 Å resolution. __Ec__PheRS is a (αβ)~2~ heterotetramer: the αβ heterodimer of __Ec__PheRS consists of 11