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Crystal structure of the Bruton’s tyrosine kinase PH domain with phosphatidylinositol

✍ Scribed by Kazutaka Murayama; Miyuki Kato-Murayama; Chiemi Mishima; Ryogo Akasaka; Mikako Shirouzu; Yasuhisa Fukui; Shigeyuki Yokoyama


Book ID
116297459
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
968 KB
Volume
377
Category
Article
ISSN
0006-291X

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Stability and folding of the SH3 domain
✍ Chen, Ya-Juan; Lin, Shih-Chieh; Tzeng, Shiou-Ru; Patel, Himatkumar V.; Lyu, Ping 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 632 KB

Bruton's tyrosine kinase (BTK) plays an important role in B cell development. Deletion of C-terminal14 amino acids of the SH3 domain of BTK results in X-linked a g ammaglobulinemia ( X U ) , an inherited disease. We report here on the stability and folding of SH3 domain of BTK. Peptides correspondin