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Crystal Structure of R 29490, an N-methylated Analog of a Potent Steroidic Gaba-A Antagonist: 3α-Hydroxy-16-Imino-5β-17-Aza-Androstan-11-One, R 5135

✍ Scribed by Thierry Boulanger; Daniel P. Vercauteren; Guy Evrard; François Durant


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
190 KB
Volume
100
Category
Article
ISSN
0037-9646

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✦ Synopsis


The synthesis of gornma-aminobutyric acid (GABA) receptor ligands is important in finding new therapeutic agerts and in helping to understand the mode of action of GABA. Amongst others, the steroid derivative 3a-hydroxy-