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Crystal structure of human ornithine decarboxylase at 2.1 å resolution: structural insights to antizyme binding

✍ Scribed by Jeffrey J Almrud; Marcos A Oliveira; Andrew D Kern; Nick V Grishin; Margaret A Phillips; Marvin L Hackert


Book ID
115629846
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
685 KB
Volume
295
Category
Article
ISSN
0022-2836

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Crystal structure of human ornithine tra
✍ Dashuang Shi; Hiroki Morizono; Mika Aoyagi; Mendel Tuchman; Norma M. Allewell 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 461 KB

The crystal structure of human ornithine transcarbamylase (OTCase) complexed with carbamoyl phosphate (CP) and L-norvaline (NOR) has been determined to 1.9-Å resolution. There are significant differences in the interactions of CP with the protein, compared with the interactions of the CP moiety of t