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Crystal structure of enantiomeric 3-amino-6,7-dihydro-6-hydroxy-5H-1,2,4-triazolo [3,4-b] 1,3-thiazine

✍ Scribed by Marek L. Główka


Publisher
Springer
Year
1994
Tongue
English
Weight
170 KB
Volume
24
Category
Article
ISSN
1572-8854

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Stereospecific synthesis of 6,7-dihydro-
✍ Yehia A. Ibrahim; Ahmed H. M. Elwahy; Ayman E. M. El-Fiky 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB

The reaction of 3-mercapto-4-aryIideneamino-l,2,4triazoles 2b-d, 3a-d with ethyl bromoacetate and/or phenacyl bromide in hot DMF and triethylamine affords the stereochemically pure 7-acyl-6-aryl-6,7dihydro-5H-lt2, 4-triazolo[3,4-b][l, 3,4]thiadiazines