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Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping

✍ Scribed by Fan Yang; Carole A Bewley; John M Louis; Kirk R Gustafson; Michael R Boyd; Angela M Gronenborn; G.Marius Clore; Alexander Wlodawer


Book ID
115629256
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
474 KB
Volume
288
Category
Article
ISSN
0022-2836

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✍ Jill Wilken; David Hoover; Darren A Thompson; Paul N Barlow; Helen McSparron; La πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 1012 KB

## Background: Rantes is a cc-type chemokine protein that acts as a chemoattractant for several kinds of leukocytes, playing an important pro-inflammatory role. entry of human immunodeficiency virus-1 (hiv-1) into cells depends on the chemokine receptor ccr5. rantes binds ccr5 and inhibits hiv-1 en