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Crystal Structure of a Template-Assembled Synthetic G-Quadruplex

✍ Scribed by Dr. Mehran Nikan; Dr. Brian O. Patrick; Prof. Dr. John C. Sherman

Book ID
112016194
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
782 KB
Volume
13
Category
Article
ISSN
1439-4227

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Template-Assembled Synthetic G-Quadruple
Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies
✍ Pierre Murat; Romaric Bonnet; Angéline Van der Heyden; Nicolas Spinelli; Pierre 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 336 KB

## Abstract A new biomolecular device for investigating the interactions of ligands with constrained DNA quadruplex topologies, using surface plasmon resonance (SPR), is reported. Biomolecular systems containing an intermolecular‐like G‐quadruplex motif **1** (parallel G‐quadruplex conformation), a