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Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

✍ Scribed by Brunger, Axel T.; Sutton, R. Bryan; Fasshauer, Dirk; Jahn, Reinhard


Book ID
109702906
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
865 KB
Volume
395
Category
Article
ISSN
0028-0836

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Crystal structure of a soluble form of h
✍ Céline Schalk-Hihi; Carsten Schubert; Richard Alexander; Shariff Bayoumy; Jose C 📂 Article 📅 2011 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 724 KB

## Abstract A high‐resolution structure of a ligand‐bound, soluble form of human monoglyceride lipase (MGL) is presented. The structure highlights a novel conformation of the regulatory lid‐domain present in the lipase family as well as the binding mode of a pharmaceutically relevant reversible inh