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Crystal structure of a nucleoside analog, 2′,3′-dideoxy-3′-azido-5-chlorocytidine

✍ Scribed by A. K. Das; S. K. Mazumdar; V. Bertolasi; A. Van Aerschot


Publisher
Springer
Year
1993
Tongue
English
Weight
246 KB
Volume
23
Category
Article
ISSN
1572-8854

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Synthesis of 3′-azido-2′,3′-dideoxy-β-D-
✍ Hansen, Poul ;Lau, Jesper ;Pedersen, Erik B. ;Nielsen, Carsten M. 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 439 KB

## Abstract The α,β‐unsaturated D‐sugar aldehyde 2, prepared from tri‐__O__‐acetyl‐D‐glucal, was converted into 1‐__O__‐acetyl‐3‐azido‐2,3‐dideoxy‐α‐D‐__arabino__‐pyranose (3) by reaction with sodium azide in a mixture of acetic acid and water followed by acetylation. Reaction of 3 with silylated p