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Crystal structure of a cold-adapted class C β-lactamase

✍ Scribed by Catherine Michaux; Jan Massant; Frédéric Kerff; Jean-Marie Frère; Jean-Denis Docquier; Isabel Vandenberghe; Bart Samyn; Annick Pierrard; Georges Feller; Paulette Charlier; Jozef Van Beeumen; Johan Wouters

Book ID
111312344
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
397 KB
Volume
275
Category
Article
ISSN
1432-1327

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The protein sequences of 18 class A 13-1actamases and 2 class C/3-1actamases were analyzed to produce a rooted phylogenetic tree using the DD peptidase of Streptomyces R61 as an outgroup. This tree supports the penicillin-binding proteins as the most likely candidate for the ancestoral origin of the