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Crystal structure of a caricain D158E mutant in complex with E-64

✍ Scribed by Nikolaos A. Katerelos; Mark A.J. Taylor; Mandy Scott; Peter W. Goodenough; Richard W. Pickersgill


Book ID
115932640
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
431 KB
Volume
392
Category
Article
ISSN
0014-5793

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Human carbonic anhydrase VII (hCA VII) is a cytosolic member of the a-CA family. This enzyme is mainly localized in a number of brain tissues such as the cortex, hippocampus and thalamus and has been noted for its contribution in generating neuronal excitation and seizures. Recently, it has been als