## Abstract The synthesis of spiroketals from nitro ketones is described. Racemic __trans__β2βMethylβ1,7βdioxaspiro[5.5]undecane (1a), and 2,8βdimethylβ1,7βdioxaspiro[5.5]undecane (1b) are synthesized as a mixture of __trans__, __trans__ and __trans__, __cis__ isomers in a ratio of 6.5:3.5 (separab
Crystal structure of 2,8-bis(bromomethyl)-1,7-dioxaspiro[5,5]undecane, an intermediate in the synthesis of analogues of a23187
β Scribed by David L. Hughes
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 115 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
An acid-catalysed rearrangement of the THP-ether of homoallylic alcohol gives ready access to an O-protected derivative of 4-hydroxytetrahydropyran and thence by two further steps to provide a short and highly stereoselective route to the title spiroketal.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Application of a novel double intramolecular hetero-Michael addition (DIHMA) strategy to spiroketal synthesis was illustrated by a concise synthesis of (Β±)-(4S\*,6S\*)-4-hydroxy-1,7-dioxaspiro[5.5]undecane, a Dacus oleae olive fly pheromone.