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Crystal Structure and Functional Analysis of the Histone Methyltransferase SET7/9

✍ Scribed by Jonathan R. Wilson; Chun Jing; Philip A. Walker; Stephen R. Martin; Steven A. Howell; G.Michael Blackburn; Steven J. Gamblin; Bing Xiao


Book ID
117269259
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
611 KB
Volume
111
Category
Article
ISSN
0092-8674

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## Abstract Histone lysine methylation is a dynamic chromatin modification that plays key regulatory roles in gene expression and other genomic functions. Methylation of Lys9 in histone H3 (H3K9) is a prominent modification that has been implicated in diverse processes, including transcriptional si