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Crystal and molecular structure of the doubly unsaturated dehydropeptide Ac-ΔPhe-Ala-ΔPhe-NH-Me

✍ Scribed by M. Rosaria Ciajolo; Angela Tuzi; Claudio R. Pratesi; Adriano Fissi; Osvaldo Pieroni


Publisher
Wiley (John Wiley & Sons)
Year
1992
Tongue
English
Weight
459 KB
Volume
32
Category
Article
ISSN
0006-3525

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An N a -protected model pentapeptide containing two consecutive DPhe residues, Boc-Leu-DPhe-DPhe-Ala-Phe-NHMe, has been synthesized by solution methods and fully characterized. 1 H-nmr studies provided evidence for the occurrence of a significant population of a conformer having three consecutive, i