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Crystal and molecular structure of N-(2,2-diethoxycarbonylvinyl)-α-d-ribofuranosylamine

✍ Scribed by Amparo Lopez-Castro; Maria Jesus Dianez Millan; Simeon Perez-Garrido


Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
278 KB
Volume
219
Category
Article
ISSN
0008-6215

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✦ Synopsis


The glycosylamines are of synthetic, biological, and pharmaceutical interest'. N-(2,2-Diethoxycarbonylvinyl)-rr-D-ribofuranosylamine

(1) was prepared from D-ribo-sylamine2, using the method described for other glycosylamines3*4. The structure was assigned on the basis of 'H-n.m.r. data, but the configuration could not be deduced; hence, an X-ray analysis has been carried out in order to confirm the structure and determine the anomeric configuration.


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Molecular and crystal structure of N-(2-
✍ Valeri V. Mossine; Charles L. Barnes; Gennadi V. Glinsky; Milton S. Feather 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 746 KB

Heyns compounds, 2-carboxymethylamino-2-deoxy-D-glucose (1), -mannose (2), and -galactose (3), were prepared by N-carboxymethylation of the corresponding hexosamines and 1 was also prepared via the reaction of D-fructose with glycine. Both 1 and 3 crystallize from aqueous solutions as zwitterions in