Crystal and molecular structure of 1,6:3,4-dianhydro-2-O-p-tolylsulfonyl-β-d-galactopyranose
✍ Scribed by An-Lai Wang; Shi-Jie Lu; Hong-Xiang Fu; Han-Qing Wang; Xiao-Ying Huang
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 380 KB
- Volume
- 281
- Category
- Article
- ISSN
- 0008-6215
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✦ Synopsis
The opening ot" oxirane rings o1' dianhydro sugars with high regiosclectivily can afford many chiral intermediates Ibr controlling asymmetric syntheses [I-5]. Here, wc report the crystal structure o1' 1,6:3,4~diallhydro-2-Ool~-lolylsullbnyl-~-D°galactopyranose (!) which may provide helpl'ul i111' o1' 1natio11 Ibr the study o1' the i'ehltionslaii~ bciwecla tile structure and NMR spectroscopic data [6].
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## Crystals of the tetrasaccharide, (2,3,4,6-tetra-0acetyl-fi-D-ghxopyranosyl~-(1 + 3)-[2,3,4,6-tetra-O-acetyI+LD-gIucopyranosyI-(1 --t 6)]-(2,4-di-0-acetyl-g\_D-glucopyranosyl)-1 --) 3)-1,2,4,6-tetrad-acetyl$?-n-ghicopyranose, belong to tge monoclinic system, space group P2,, with a = 12.709(4),
1,2:3,4-Di-O-isopropylidene-6-O-toluene-p-s~fonyl-~-D-g~a~op~~ose has been investigated by X-ray diffraction methods. The crystals are orthorhombic, space group p2,2,2, (2 = 4) with cell dimensions a = 15.210( 2), b = 15.658(2), and c = 8.858(l) A. The structure was solved by direct methods and the
The title compound was isolated by several recrystallisations from a 1:l mixture of diastereomers which was obtained in 75% yield from the reaction of 1,2:3,4-di-O-isopropylidene-c~-D-galactopyranose with epichlorohydrin. The absolute configuration of this isomer (30% yield) was established by X-ray