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Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

โœ Scribed by Zhang, Eric E; Liu, Yi; Dentin, Renaud; Pongsawakul, Pagkapol Y; Liu, Andrew C; Hirota, Tsuyoshi; Nusinow, Dmitri A; Sun, Xiujie; Landais, Severine; Kodama, Yuzo


Book ID
109926309
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
559 KB
Volume
16
Category
Article
ISSN
1078-8956

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## Abstract Acute promyelocytic leukemia (APL) cells are characterized by PML/RARฮฑ fusion protein, high responsiveness to arsenic trioxide (ATO)โ€induced cytotoxicity and an abundant generation of reactive oxygen species (ROS). In this study we investigated the association among these three features