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Cryptic chromosomal aberrations waiting to be discovered

โœ Scribed by Lahortiga, I; Cools, J


Book ID
110056599
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
57 KB
Volume
20
Category
Article
ISSN
0887-6924

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## Abstract The translocation t(8;21)(q22;q22), which results in the fusion of the __AML1__ (__RUNX1__) and __ETO__ (__CBFA2T1__) genes, is a recurrent aberration in acute myeloid leukemia (AML), preferentially correlated with FAB M2, and has the highest incidence in childhood AML. Because of the f