Crown Ethers in Enantioselective Synthesis
β Scribed by L. Tbke; P. Bako; Gy. Keglevich; T. Bako
- Book ID
- 101975576
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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The sulfuric acid-promoted reaction of benzo-15-crown-5 O) and benzo-18-crown-6 (6) with aliphatic aldehydes, leading to the formation of anthracene crown et~rs, was studied. A substantial substiment effect on the reaction comse was found. For the isdmtyi group the highest yield was obtained, while
Che synthesis and chemistry of macrocyclic polyethers are currently receiving a great deal of attention. Very recently Cram and co-workers 132 have reported the synthesis of two crown ethers (3,~ and QJ). We have prepared two series of novel crown ethers in which respectively, the 1,3and 2,5-positio