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Crosstalk between site-specific modifications on p53 and histone H3

✍ Scribed by Warnock, L J; Adamson, R; Lynch, C J; Milner, J


Book ID
110072774
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
194 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract In mammalian cells, induction of immediate‐early (IE) gene transcription occurs concomitantly with histone H3 phosphorylation on Ser 10 and is catalyzed by mitogen‐activated protein kinases (MAPKs). Histone H3 is an evolutionarily conserved protein located in the core of the nucleosome,