✦ LIBER ✦
Crossover reaction between mianserin and trazodone for restless legs syndrome
✍ Scribed by Koichi Otani; Sunao Kaneko
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 160 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
✦ Synopsis
A 58-year-old woman with a past history of mianserin-induced restless legs syndrome (RLS) developed the same syndrome on subtherapeutic doses of trazodone. However, neither nortriptyline nor imipramine at therapeutic doses caused RLS. The present report suggests that hyposerotonergic states are involved in the pathophysiology of RLS.