Crosslinking of Trimethylene Carbonate and D, L-Lactide (Co-) Polymers by Gamma Irradiation in the Presence of Pentaerythritol Triacrylate
✍ Scribed by Erhan Bat; Theo G. van Kooten; Jan Feijen; Dirk W. Grijpma
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 594 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1616-5187
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✦ Synopsis
Abstract
High‐molecular‐weight (co)polymers of trimethylene carbonate and D,L‐lactide are efficiently crosslinked using PETA during gamma irradiation. Form‐stable networks with gel contents of 86 ± 5 to 96 ± 1 are obtained from non‐crystalline (co)polymers. Glass transition temperatures and elastic moduli of the networks can be varied by adjusting the copolymer composition. The PETA‐containing (co)polymer networks are not cytotoxic. Upon incubation in macrophage cultures for 14 d, all (co)polymer films and PETA‐containing network films erode to varying extents, showing that these materials can be degraded by cell‐mediated erosion processes. This method is very useful for the facile preparation of TMC‐ and DLLA‐containing form‐stable networks from high‐molecular‐weight polymers. magnified image