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Crosslinking of gelatin-based drug carriers by genipin induces changes in drug kinetic profiles in vitro

✍ Scribed by Goutam Thakur; Analava Mitra; Dérick Rousseau; Amit Basak; Siddik Sarkar; Kunal Pal

Book ID
106400550
Publisher
Springer
Year
2010
Tongue
English
Weight
572 KB
Volume
22
Category
Article
ISSN
0957-4530

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Genipin-crosslinked gelatin microspheres
Genipin-crosslinked gelatin microspheres as a drug carrier for intramuscular administration:In vitro andin vivo studies
✍ Liang, Huang-Chien ;Chang, Wen-Hsiang ;Lin, Ko-Jung ;Sung, Hsing-Wen 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB

## Abstract Gelatin microspheres have been widely evaluated as a drug carrier. Nevertheless, gelatin dissolves rather rapidly in aqueous environments, making the use of the polymer difficult for the production of long‐term delivery systems. This adverse aspect requires the use of a crosslinking age