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Crosslink Analysis of N-Terminal, C-Terminal, and N/B Determining Regions of the Moloney Murine Leukemia Virus Capsid Protein

✍ Scribed by Jason McDermott; Sonya Karanjia; Zachary Love; Eric Barklis


Book ID
112272883
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
312 KB
Volume
269
Category
Article
ISSN
0042-6822

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Reverse transcriptase (RT) is a modular enzyme carrying polymerase and ribonuclease H (RNase H) activities in separable domains. Retroviral replication requires both of these activities. The RNase H domain is responsible for hydrolysis of the RNA portion of RNAβ€’DNA hybrids, and this activity require